O cenário é no mundo interior de um sistema de computador conhecido por seus habitantes como Mainframe. Ele foi deliberadamente escolhido devido a restrições de tecnológicas da época, como o mundo da informática ficcional permitido para blocos de modelos de aparência e animação mecânica A maioria dos episódios estabelece personagens, locais e elementos da história, como os cubos de jogo gigantescos. Quando o usuário carrega um jogo, um cubo de jogo fica em um local aleatório no Mainframe, isolando-a do resto do sistema e transformando-o em um gamescape. Bob freqüentemente entra nos jogos, reinicia a tornar-se um personagem do jogo, e luta contra o caráter do usuário para salvar o setor. Se o usuário ganha um jogo, o setor do cubo caiu é destruído, e os sprites e binomes que foram pegos dentro são transformados em parasitas semelhantes a vermes, que consomem energia chamados nulos.
Paul Dobson • Sharon Alexander • Kathleen Barr • Ian James Corlett • Giacomo Baessato • Shirley Milliner • Scott McNeil • Garry Chalk
Megabyte tries to blackmail Bob into stabilizing a tear into a portal to the super computer. As Bob makes an escape with the help from Dot the user inserts a game which stabilizes the tear. Bob and the rest of the sprites must race Megabyte, who has infected the user, to the portal to win the game and keep him from gaining access to the super computer.
Megabyte takes advantage of Enzo's new delivery service to try to deliver a delete command to Hexadecimal. Bob unknowingly attempts to deliver the package, only to be trapped in a racing game where the user's vehicle becomes a ticking time-bomb.
An accident causes a magnet to drain Dot of energy and, according to Phong, the only way to save her is to feed her slow food from Al's on level 31. While in Al's, the sprites are caught in a medival fantasy game where Bob and the user are attempting to reach Dot, the damsel in distress. Or are they?
Megabyte steals Hexadecimal's precious Medusa Bug but finds it to be a trap which turns everything in Mainframe to stone.
After Bob makes Dot late for an appointment, she and Bob get into a big argument. Seems Dot suddenly thinks Bob is too "random", and Bob thinks Dot is too straight-laced. Enzo and the other citizens of Mainframe try to trick the two into making up, but nothing seems to work. When Bob and Dot get trapped in a game cube, will that be enough of a crisis to get them to stop squabbling?
Frisket swallows an unformat command Megabyte had just uncovered. Wanting to get it back, the virus has Enzo kidnapped, using him as bait to lure the dog into Silicon Tor.
Mainframe is attacked by dastardly software pirates, who quickly scavenge the city, taking everything of worth - including Bob!
After Bob upstages him during a game, Enzo decides to get smarter in a hurry. The Read-Only Room at the Principle Office is too much like work for the young sprite, so he's tempted into tinkering with the system clock. Only instead of making himself twice as smart as everyone else in Mainframe, he accidentally makes everyone else half as smart! What's worse, he ends up trapped in a game cube with a bunch of his dumbed-down friends. Can Enzo best the user by himself and fix this mess?